BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

The introduction and six essays in this book originally appeared as a continuing series in the Southern Journal of Philosophy, and are gathered together here for the first time in one volume. In the introduction, E. M. Adams briefly touches upon the major questions of the philosophy of mind and how they have been dealt with in the past; his suggestion for the future is that philosophers give themselves a little more "categorial room" in which to handle these problems. In (...) the first essay Douglas Browning argues for the essential privacy of the verbal and adverbial functionings of feeling. This is followed by an essay by Charles Hartshorne in which he argues that feelings are by no means essentially private, and that in fact God shares all of our feelings in their full totality. The essay by Donald F. Gustafson continues the non-privacy argument in a different mode. He argues that there is an essential connection between feeling and the expression of that feeling, and that keeping feelings to oneself is something that is learned and by no means necessary. I am not sure his rather narrow notion of privacy keeps the argument philosophically interesting, however. In contrast, the fourth essay, by Erwin W. Straus, is basically phenomenological, and, unfortunately, sounds more like a polemic than a clear description of the incommensurability between the lived world and the "scientific world." In the fifth essay Edward H. Madden gives a synoptic view of the recent work in the philosophy of mind by C. J. Ducasse. Madden sees in his work an extremely promising analysis of the problems in this field, and attempts to show why this is so. The most interesting essay in this book is, I found, the last, by the editor, in which he adds another discussion of Strawson's concept of a person. Van de Vate argues that the analogy upon which Strawson launches his account is misleading. Rather than seeing the concept of a person allied with a tool of the sort Wittgenstein described, Van de Vate would have us understand it in the light of public tools like parliaments. From here, Van de Vate argues that persons are not natural facts, but social facts. I should like to see a more complete handling of this idea and its problems at some future date.--W. de V. (shrink)

Author list: H. Frey; A. Willwoll; Georg Wunderle; E. Raitz V. Frentz; Q. Wihstutz; G. Wihstutz; R. Walter; A. Bolley; E. Steinwand; R.H. Thouleß; B. Vasady; A. Bolley.

The Kiki-Bouba effect comprises a relation between two abstract figures and two non-words: the star-shaped figure is called 'Kiki' and the rounded figure 'Bouba'. The effect is explained by a sound-vision synaesthesia: certain sounds are associated with certain shapes in a non-arbitrary manner.When we asked the participants to decide which of the two figures, the star-shaped or the rounded one, to call yin and which yang, some 85% choose the star-shaped figure as yin. There are previous cases of synaesthesia where (...) personality is attributed to numbers or letters. In our results, the word Kiki is overall happy, clever, small, thin, young, unpleasant, and nervous. The starshaped figure is overall clever, tall, small, slim, nervous, unpleasant, and upper-class. That is, the correspondence above all concerns the qualifying adjectives clever, unpleasant, and nervous, as well as the physical appearance small and thin. This brings us to the fat-thin effect. Cinema, literature, comics, and children's programmes are full of contrasting figures: Don Quixote and Sancho Panza, Laurel and Hardy , Asterix and Obelix, Tintin and Captain Haddock, Bert and Ernie , or the Spanish comic about very naughty twin boys called Zipi and Zape . Our main conclusion is that first names and last names are not entirely arbitrary. There is a correspondence between names and physical characteristics and concepts . The Kiki-Bouba effect is a semantic one. (shrink)

Afshar et al. claim that their experiment shows a violation of the complementarity inequality. In this work, we study their claim using a modified Mach-Zehnder setup that represents a simpler version of the Afshar experiment. We find that our results are consistent with Afshar et al. experimental findings. However, we show that within standard quantum mechanics the results of the Afshar experiment do not lead to a violation of the complementarity inequality. We show that their claim originates from a particular (...) technique they use to analyze their results. In their analysis, they assume a classical concept, that particles have a definite trajectory before detection, thus, they obtain which-way information by particle detection plus path extrapolation by applying momentum conservation. This analysis technique is standard in experimental particle physics. Important discoveries such as the detection of vector bosons have been made through the application of this technique. We note that particle detection plus path extrapolation is a suitable technique within de Broglie-Bohm theory of quantum mechanics. (shrink)

A survey of works on automatic theorem-proving in the ussr 1964-1970. the philosophical problems are not touched.

Here are the 18 guidance points contained in the UNAIDS document on Ethical Considerations in HIV Preventive Vaccine Research, reproduced by kind permission of the Joint United Nations Programme on HIV/AIDS.

The λσ-calculus adds explicit substitutions to the λ-calculus so as to provide a theoretical framework within which the implementation of functional programming languages can be studied. This paper generalises the λσ-calculus to provide a linear calculus of explicit substitutions, called xDILL, which analogously describes the implementation of linear functional programming languages.Our main observation is that there are non-trivial interactions between linearity and explicit substitutions and that xDILL is therefore best understood as a synthesis of its underlying logical structure and the (...) technology of explicit substitutions. This is in contrast to the λσ-calculus where the explicit substitutions are independent of the underlying logical structure. (shrink)

REVISTA EDUCAÇÃO E FILOSOFIA é uma publicação semestral do Departamento de Pedagogia da Universidade Federal de Uberlândia. Este número é o primeiro fruto de um sonho antigo e de um inconformismo com a falta de um veículo como este, entre nós. Pretendemos incentivar e divulgar trabalhos de natureza interdisciplinar nas áreas de Educação e Filosofia. Mas, se a Revista vier a ter uma linha preferencial — e isto depende muito mais dos nossos colaboradores, que da direção — essa linha não (...) será exclusiva nem excludente, pois a Revista estará aberta às mais diversas correntes de pensamento, não se fechando, pois, com quaisquer grupos. Isto é consequência de nossa visão de Universidade como lugar onde se deve estimular a heterogeneidade de tendências e o debate. Entendemos que uma filosofia que propugne posições dogmáticas inviabiliza o debate sobre seus próprios pressupostos, deixando de ser filosofia para tornar-se mera ideologia. Ademais, a discussão de questões de princípio tem razão de ser e há momentos em que apenas ela pode contribuir para a superação de impasses de ordem teórica ou prática, sobretudo nas ciências sociais; somente uma abordagem crítica — o que equivale a dizer: sem preconceitos — pode contribuir para os debates de questões fundamentais tanto para a filosofia, quanto para a educação, ou ainda quanto para uma filosofia de educação. A REVISTA EDUCAÇÃO E FILOSOFIA deve representar um fórum de permanentes debates aberto a todo educador, todo pensador e, sobretudo, a todo pensador-educador. Propomo-nos a acolher e divulgar contribuições que sintetizem os resultados de investigações empíricas e teóricas e de projetos práticos, preferencialmente, mas não exclusivamente, desenvolvidos na região do Triângulo Mineiro. Dentro do princípio de que o caráter objetivo e preciso do conhecimento científico não é incompatível com os conformismos diante das injustiças de toda ordem, pretendemos, ainda, ser um estímulo aos balanços críticos. A REVISTA EDUCAÇÃO E FILOSOFIA é a soma do que temos e somos, mas será um veículo para atingirmos aquilo que queremos ser e ter. Deverá abrir caminho para a reflexão filosófica, a reflexão sobre educação, a reflexão sobre o ensino da filosofia e possibilitará o diálogo com os pensadores e educadores presentes e pretéritos visando à construção do futuro. Nós não teríamos sido justos se olvidássemos o empenho da professora Carmelita Vieira dos Santos, chefe do Departamento de Pedagogia para que, diante de tantos cortes de recursos, fossem mantidos aqueles destinados à revista. Nossos agradecimentos também à professora Marly Bernardes de Araújo, diretora do Centro de Ciências Humanas e Artes. Ao Conselho do Departamento de Pedagogia, nossa gratidão por ter acolhido a Revista. (shrink)

Este artigo parte da hipótese de que o conceito de sujeito transcendental envolve pressupostos teóricos da física clássica. Em seguida, a partir da reformulação feita por Schopenhauer do conceito de sujeito transcendental em Kant, procuramos mostrar como a física moderna acarreta a necessidade de revisão de tal conceito, na medida em que reformula noções como espaço-tempo, matéria e causalidade. Para tal propósito recorremos à noção de monismo neutro, um tipo de materialismo não-reducionista, defendido por Bertrand Russell e Michael Lockwood.

Vor-Worte.--Religion und Psychologie.--Not und Hilfe.--Der Liebe in der Aufbauordnung des Stifterschen Menschenbildes.--De profundis ; eine Auseinandersetzung mit C.G. Jung, Herbst 1945.--Christentum und Humanismus ; ein Gespräch mit Erziehern.

Some authors of Jurisprudence, especially Michel Villey, tried to present what they thought to be the aristotelic theory of justice, grounding in it their own theories. To Villey, pecifically, “the right” would be the correct translation of the Greek to dikaion. To defend, based on Aristotle, a conception of the just that refuses subjective elements of a theory of action is an error. And this error lies in ignoring a redefinition of to dikaion made by Aristotle in Chapter 9 of (...) Book V of Nicomachean Ethics. There, Aristotle adds to the objective conditions of the just and the unjust (EN V, 1-7) some subjective conditions referring to person who suffers the action. Only after correctly understanding these conditions we will be able to correctly understand the aristotelic theory of justice. As Villey and other authors ignore it, they err interpreting Aristotle and using him to found their own theories. (shrink)

This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Biomedical Informatics: We Are What We Publish", written by Peter L. Elkin, Steven H. Brown, and Graham Wright. It is introduced by an editorial. This article contains the combined commentaries invited to independently comment on the Elkin et al. paper. In subsequent issues the discussion can continue through letters to the editor.

A scholarly edition of The Clarendon Edition of the Works of John Locke: Correspondence: Letters 1702-2198 by E. S. de Beer. The edition presents an authoritative text, together with an introduction, commentary notes, and scholarly apparatus.